Cryopreservation of unilateral ovarian biopsies in the form of tissue is currently practiced before chemo/radiotherapies and in some benign diseases, although it is not common. Freezing tissue from the ovaries can provide a chance for future fertility and hormone production in children and adults undergoing treatment for cancer or other diseases that affect the ovaries. The egg-producing tissue from the ovary is removed, frozen, and stored. When the treatment is completed and the patient wishes to become pregnant or have normal hormone production resume, the frozen tissue is thawed and transplanted into her pelvic. Its biggest advantages are that it does not need sperm and egg stimulation treatments called hyperstimulation. It is the only fertility preservation method, especially in pre-pubertal girls. These re-transplanted tissues continue to fulfill their endocrine functions over 90%.

In recent years, the material removed after endometrioma operations was dissected under a stereomicroscope in the embryology laboratory, and healthy ovarian regions around the cyst wall were tried to be distinguished, and these parts could be frozen and stored appropriately. Besides providing a chance for future fertility and hormone production, this technology will be used effectively in the treatment of menopausal symptoms in time.